The villa, built among the gentle hills of Colle Umberto, was the residence of the Doges Morosini from Venice.
In 1850, when the villa was purchased by the Counts Lucheschi, it was expanded with the construction of two barchesse, contributing to give it a more modern appearance. For about a year during World War I, the villa became the headquarters of the Austro-Hungarian Air Force's supreme command. In June 1918, it was repeatedly targeted by Italian artillery, without being damaged.
After the war, it was completely restored with significant work, which lasted until 1924. The imposing Morosini-Lucheschi Patrician Villa reflects the architecture of Palladian villas, even though it was built in the neoclassical era.
The villa is cataloged among the "Venetian villas" and is under the jurisdiction of the Artistic Superintendency of Venice.