Originally titled S. Croce di Campestrino, it is the first church of the Christian community of Belluno. Built outside the urban perimeter in the Roman cemetery area along the road – via Rivizzola – that led to the bridge over the Ardo and from there towards Cadore: therefore likely predating the edict of 313 with which Constantine allowed the profession of the Christian faith.
In ancient times it was known as the Church of S. Croce in Campestrino, from the name of the place where it stood. The building underwent numerous reconstructions and alterations, but still retains the Greek cross plan dating back to the 6th century.
Next to it stood a hospice that from 1184 until 1793 also served a health function as a lazaretto. Between the 13th and 14th centuries, it hosted a small Cistercian community, linked to the abbey of Follina. The church was documentedly reconstructed for the first time in 1358 and then again in 1631.
Inside, there is a series of wooden altars from the 17th century, with paintings by Francesco Frigimelica and others.